Comparative Genome and Network Centrality Analysis to Identify Drug Targets of Mycobacterium tuberculosis H37Rv

Table 4

Genes reported as virulence factors.

Gene name	Rv number	Functional class	Betweenness	Eigenvector	Degree	Closeness
sigA	Rv2703	Information pathways	56665.156	0.004549677	80	0.04838473
katG	Rv1908c	Virulence, detoxification, and adaptation	50548.035	0.005637622	76	0.048456423
icl1	Rv0467	Intermediary metabolism and respiration	23928.854	0.002939687	53	0.048157435
pafA	Rv2097c	Intermediary metabolism and respiration	19334.732	0.00727773	57	0.048266105
ideR	Rv2711	Regulatory proteins	15661.199	0.005902891	41	0.04817209