Phenotypic Characteristics Associated with Virulence of Clinical Isolates from the Sporothrix Complex
Correlation between melanization and thermotolerance in the Sporothrix complex. (a) The growth inhibition of the strains is not dependent on their levels of DHN-melanin. (b) Tricyclazole, a DHN-melanin inhibitor, is able to enhance fungal growth inhibition. (c) L-DOPA and (d) L-tyrosine, precursors for eumelanin and pyomelanin, respectively, are able to reduce growth inhibition in some strains.