Figure 2: Images from a 61-year-old female with a cough and chest pain for 2 months. (a) B-mode sonogram showed a  cm lesion (M) with hypoecho texture in inferior lobe of right lung. (b) CEUS obtained 12 seconds after administration of SonoVue showed a lesion with complete absence of enhancement (M). (c) CEUS obtained 1 minute and 27 seconds after injection of SonoVue showed that the lesion still had absence of enhancement (M). Biopsy was cancelled because no neoplasm was revealed on CEUS. CT scan conformed that the whole lesion represented as necrosis tissue.