Hypoxia-Induced Epithelial-Mesenchymal Transition Is Involved in Bleomycin-Induced Lung Fibrosis

Figure 2

Protein levels of E-cadherin and vimentin in lung tissues of mice administered with bleomycin. The lung tissues of C57BL/6J mice were collected 1, 3, and 6 weeks following intratracheal bleomycin or saline instillation. (a) Immunofluorescence staining of E-cadherin and vimentin expression in lung tissue sections. Positive E-cadherin and vimentin staining was observed at the distal alveoli. (b) Representative Western blots of E-cadherin, N-cadherin, and vimentin protein in lung tissues. (c) Semiquantitative assay of Western blots of E-cadherin protein and vimentin protein expression in lung tissues. , , and versus control. .

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