Hypoxia-Induced Epithelial-Mesenchymal Transition Is Involved in Bleomycin-Induced Lung Fibrosis

Figure 3

Protein expression of signal molecules in lung tissues. (a) Representative Western blots of protein expression in lung tissues. (b) Semiquantitative HIF-1α expression from densitometry analysis of bands in lung tissues. versus control; . (c) Semiquantitative ZEB1 expression in lung tissues. versus control; . (d) Semiquantitative phospho-p44/42 protein expression in lung tissues. versus control; . (e) Semiquantitative phospho-p38 MAPK protein expression in lung tissues. , versus control; . (f) Semiquantitative assay of Western blots of CD44 protein expression in lung tissues. (g) Immunohistochemical staining of CD44 protein. CD44 positive cells were obviously increased in alveoli in mice that received intratracheal bleomycin administration 1 week after treatment.

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