Comparison of Intravoxel Incoherent Motion Diffusion-Weighted MR Imaging and Arterial Spin Labeling MR Imaging in Gliomas
Table 3
Histogram parameters of solid component in tumor from the ASL and MB-DWI from histogram analysis as well as ROC analysis in HGG and LGG (mean ± SD).
Tumor
HGG
LGG
Test type
AUC
Cutoff
CBF
Mean (mL/100 g/min)
102.04 ± 45.55
62.26 ± 18.13
0.011
tt
0.783
Median (mL/100 g/min)
99.65 ± 42.08
62.59 ± 18.07
0.011
tt
0.801
Maximum (mL/100 g/min)
160.77 ± 80.72
91.27 ± 30.89
0.002
mw
0.85
81
Minimum (mL/100 g/min)
54.08 ± 30.13
31.64 ± 8.96
0.022
tt
0.738
90th percentile (mL/100 g/min)
132.15 ± 68.18
78.91 ± 25.35
0.015
mw
0.787
Standard deviation (mL/100 g/min)
22.51 ± 16.07
13.15 ± 5.77
0.035
mw
0.755
Skewness
0.22 ± 0.32
−0.06 ± 0.25
0.024
tt
0.79
Kurtosis
2.92 ± 0.76
2.64 ± 0.44
0.649
mw
0.559
Mean ( mm2/s)
5.1 ± 3.39
2.77 ± 0.69
0.002
mw
0.857
3.5
Median (10−3 mm2/s)
3.54 ± 1.52
2.58 ± 0.33
0.002
mw
0.85
Maximum (10−3 mm2/s)
30.28 ± 21.91
9.38 ± 8.72
0.015
mw
0.79
Minimum (10−3 mm2/s)
0.84 ± 0.76
1.46 ± 0.77
0.03
mw
0.238
90th percentile (10−3 mm2/s)
9.86 ± 10.22
4.02 ± 1.46
0.006
mw
0.825
Standard deviation (10−3 mm2/s)
3.39 ± 3.35
13.8 ± 1.58
0.055
mw
0.734
Skewness
2.81 ± 1.93
1.66 ± 1.3
0.186
mw
0.664
Kurtosis
19.93 ± 20.46
10.04 ± 4.96
0.569
mw
0.573
Mean (10−3 mm2/s)
0.69 ± 0.09
0.81 ± 0.12
0.013
tt
0.818
Median ( mm2/s)
0.69 ± 0.09
0.82 ± 0.11
0.006
mw
0.825
0.755
Maximum (10−3 mm2/s)
0.98 ± 0.19
1.07 ± 0.15
0.15
mw
0.678
Minimum (10−3 mm2/s)
0.29 ± 0.25
0.55 ± 0.25
0.039
tt
0.755
90th percentile (10−3 mm2/s)
0.83 ± 0.14
0.95 ± 0.11
0.029
tt
0.766
Standard deviation (10−3 mm2/s)
0.12 ± 0.05
0.12 ± 0.08
0.776
mw
0.465
Skewness
−0.45 ± 1.23
−0.42 ± 1.39
0.955
mw
0.49
Kurtosis
6.63 ± 5.09
5.12 ± 6.53
0.063
mw
0.273
Mean (10−3 mm2/s)
0.4 ± 0.11
0.49 ± 0.1
0.039
tt
0.769
Median (10−3 mm2/s)
0.39 ± 0.12
0.49 ± 0.11
0.025
tt
0.783
0.395
Maximum (10−3 mm2/s)
0.81 ± 0.18
0.84 ± 0.14
0.82
mw
0.528
Minimum (10−3 mm2/s)
0.14 ± 0.07
0.22 ± 0.12
0.042
tt
0.766
90th percentile (10−3 mm2/s)
0.57 ± 0.16
0.67 ± 0.15
0.14
tt
0.678
Standard deviation (10−3 mm2/s)
0.13 ± 0.05
0.14 ± 0.05
0.728
tt
0.528
Skewness
0.73 ± 0.69
0.29 ± 0.49
0.09
tt
0.297
Kurtosis
4.22 ± 2.83
2.89 ± 1.04
0.11
tt
0.301
ADC
Mean (10−3 mm2/s)
0.85 ± 0.09
1.04 ± 0.13
0.001
tt
0.85
Median ( mm2/s)
0.85 ± 0.11
1.07 ± 0.12
0.000
mw
0.92
0.885
Maximum (10−3 mm2/s)
1.37 ± 0.29
1.42 ± 0.21
0.648
tt
0.58
Minimum (10−3 mm2/s)
0.43 ± 0.27
0.65 ± 0.28
0.054
tt
0.75
90th percentile (10−3 mm2/s)
1.07 ± 0.17
1.24 ± 0.16
0.019
tt
0.76
Standard deviation (10−3 mm2/s)
0.16 ± 0.07
0.17 ± 0.05
0.528
tt
0.6
Skewness
0.23 ± 1.5
−0.16 ± 0.89
0.457
tt
0.35
Kurtosis
6.67 ± 5.11
3.35 ± 1.95
0.04
tt
0.21
Statistically significant values are presented in bold font. mw: Mann-Whitney test, tt: Student’s -test. LGG: low grade gliomas, AUC: area under the curve.
