Association between Genetic Polymorphisms of DNA Repair Genes and Chromosomal Damage for 1,3-Butadiene-Exposed Workers in a Matched Study in China
Table 4
Chromosomal damage between diplotypes of XRCC1 in BD-exposed workers.
Diplotypes
(%)
MN ()
NPB ()
NBUD ()
NDI
TCGG-TCGG
9 (20.0)
8.89 ± 4.40
2.44 ± 2.01
1.89 ± 1.27
2.21 ± 0.17
TCGG-CCGG
7 (15.6)
6.14 ± 3.13
2.00 ± 2.38
3.43 ± 1.98
2.11 ± 0.09
TCGG-TCAG
5 (11.1)
7.00 ± 2.24
3.60 ± 4.04
2.60 ± 1.67
2.22 ± 0.14
TCGA-CCGG
5 (11.1)
8.50 ± 2.89
4.25 ± 2.87
4.25 ± 2.06*
2.07 ± 0.11
TCGG-TCGA
4 (8.9)
11.60 ± 4.61
2.40 ± 0.55
5.80 ± 3.56*
2.25 ± 0.05
Others
15 (33.3)
7.33 ± 3.54
2.20 ± 3.43
2.73 ± 2.19
2.25 ± 0.13
The diplotype is defined as the allele present at positions −77 (C/T), 194 (C/T), 280 (G/A), and 399 (G/A), respectively. *As seen in Table 5, P < 0.05.
