Clinical Study

Effluent Tenascin-C Levels Reflect Peritoneal Deterioration in Peritoneal Dialysis: MAJOR IN PD Study

Table 4

Test performance of effluent biomarker cut-off levels to diagnose the high category of the PET.

BiomarkerCut-off levelSensitivitySpecificityFalse negativeAUC

Tenascin-C5.7 ng/mL100%42%0%0.71
6.0 ng/mL92%43%1.3%
6.5 ng/mL85%48%3.6%

Matrix metalloproteinase-2213 ng/mL93%79%0.8%0.91
250 ng/mL86%87%1.4%
270 ng/mL79%88%2.0%

AUC: area under curve.