Clinical Study
Effluent Tenascin-C Levels Reflect Peritoneal Deterioration in Peritoneal Dialysis: MAJOR IN PD Study
Table 4
Test performance of effluent biomarker cut-off levels to diagnose the high category of the PET.
| Biomarker | Cut-off level | Sensitivity | Specificity | False negative | AUC |
| Tenascin-C | 5.7 ng/mL | 100% | 42% | 0% | 0.71 | 6.0 ng/mL | 92% | 43% | 1.3% | 6.5 ng/mL | 85% | 48% | 3.6% |
| Matrix metalloproteinase-2 | 213 ng/mL | 93% | 79% | 0.8% | 0.91 | 250 ng/mL | 86% | 87% | 1.4% | 270 ng/mL | 79% | 88% | 2.0% |
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AUC: area under curve.
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