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BioMed Research International
Volume 2015 (2015), Article ID 245080, 4 pages
http://dx.doi.org/10.1155/2015/245080
Research Article

Own Experience in Treatment of Patients with Penile Cancer Using Photodynamic Therapy

P.A. Herzen Moscow Cancer Research Institute, 2nd Botkinskiy Proezd 3, Moscow 125284, Russia

Received 24 April 2014; Revised 7 August 2014; Accepted 26 August 2014

Academic Editor: Michael S. Kaminer

Copyright © 2015 Elena Filonenko et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Penile cancer is a rare pathology. For penile cancer surgical treatment, radiotherapy, chemotherapy, and combined modality treatment are available. Because of great importance of this organ for mental condition of patient, the development of organ-preserving methods allowing to minimize impact on patient’s quality of life without compromising of oncological results is desirable. In the Center of Laser and Photodynamic diagnosis and treatment of tumors in P.A. Herzen Moscow Cancer Research Institute the methods of photodynamic therapy in patients with penile cancer have been developed. From 2011 to 2013 the treatment was conducted in 11 patients with precancer and cancer of penile. The average age was 56.6. According to morphological diagnosis photodynamic therapy (PDT) was performed using two methods. One method included topical application of agent for PDT and the second intravenous administration of photosensitizer. For topical application alasens was used and for intravenous injection we applied radachlorine. All patients had no complications. Complete regression was achieved in 9 patients, and partial regression in 2. Thus, the results showed that photodynamic therapy for penile cancer stage Tis-1N0M0 permits performing organ-preserving treatment with satisfactory oncological results and no impairment of patient’s quality of life.