In Vivo Anti-Candida Activity of Phenolic Extracts and Compounds: Future Perspectives Focusing on Effective Clinical Interventions

Table 3

Phytochemical preparations evaluated through in vivo laboratorial models.

Application	In vivo model	Type of formulation	Reference
Intraperitoneal	Immunomodulation	Solution (water)	[65]
	Intravenous Candida infection	Solution (methanol)	[77]
		Suspension (methanol)	[75]
Intravaginal	Vaginal infection	Cream (o/w emulsion)	[70]
		Suspension	[79]
Intravenous	Intravenous Candida infection	Solution (water)	[78]
Orally	Anti-inflammation, antinociceptive and would healing potential (incision/excision models)	Suspension (0.5% sodium carboxy methyl cellulose (CMC))	[72]
	Excision and incision wound	Suspension (extract in vehicle)	[74]
	Immunomodulation	Suspension (1% sodium carboxy methyl cellulose (CMC))	[66]
		Suspension (1% w/v aqueous gum acacia)	[67]
	Intravenous Candida infection	Solution (aqueous)	[76]
	Oral cavity children affections	Mouthwash (water)	[81]
	Subclinical mastitis	Crude extracts (cooked and powder leaves)	[80]
Topically	Excision and incision wound	Ointment (vehicle)	[72]
		Cream (aqueous)	[71]
	Excision wound	Cream (aqueous)	[73]
		Ointment (w/w)	[69]
		Ointment (w/w)	[90]
		Ointment (vehicle)	[68]