Role of Inhibitors of Apoptosis Proteins in Testicular Function and Male Fertility: Effects of Polydeoxyribonucleotide Administration in Experimental Varicocele

Figure 4

High-power-view light micrograph of a left testis harvested from sham-operated rats and varicocele rats administered with vehicle (1 mL/kg, i.p.), PDRN (8 mg/kg, i.p.), DMPX (0.1 mg/kg, i.p.) plus PDRN (8 mg/kg, i.p.), varicocelectomy alone, or varicocelectomy plus PDRN (8 mg/kg, i.p.) at day 21 showing survivin immunostaining (original magnification ×200). Arrowheads show positive cells.

(a) Sham

(b) Varicocele + vehicle

(c) Varicocele + PDRN

(d) Varicocelectomy

(e) Varicocelectomy + PDRN

(f) Varicocele + DMPX + PDRN