Polymorphic Basal Rates of Continuous Subcutaneous Insulin Infusion among Taiwanese Children with Type 1 Diabetes
Table 3
Insulin dose at continuous subcutaneous insulin infusion (CSII) therapy.
All stages
Stage 1 or 2
Stage 3 or 4
Stage 5
Young adult (>18 years old)
Prepump TDD (U/kg)
1.13 ± 0.42
1.13 ± 0.37
1.00 ± 0.29
1.25 ± 0.53
1.01 ± 0.23
0.382
Postpump TDD (U/kg)
0.87 ± 0.22*
0.95 ± 0.23
0.85 ± 0.18
0.87 ± 0.25*
0.78 ± 0.14*
0.438
Chang of TDD (%)
20.8 ± 22.8
10.8 ± 22.5
21.1 ± 32.9
25.4 ± 19.4
21.6 ± 14.1
0.233
Basal insulin (U/kg/day)
0.31 ± 0.07
0.32 ± 0.08
0.34 ± 0.08
0.31 ± 0.07
0.27 ± 0.04
0.252
Basal insulin proportion (% of TDD)
36.5 ± 6.3
33.6 ± 4.7
39.6 ± 6.4
36.8 ± 6.3
35.5 ± 7.1
0.226
C/I
10.2 ± 4.2
12.9 ± 5.4
12.7 ± 4.8
9.0 ± 2.6
7.3 ± 1.5
0.001**
ISF
56.4 ± 13.6
66.7 ± 15.0
61.2 ± 13.5
52.5 ± 11.7
48.1 ± 8.0
0.001**
Data are mean ± standard deviation or percentage. *Significant difference () as compared with the prepump TDD by paired -test (two-tailed). for linear trend <0.05 by ANOVA test. TDD: total daily dose; C/I: carbohydrate to insulin ratio; ISF: insulin sensitivity factor.
