Effects of P-15 Peptide Coated Hydroxyapatite on Tibial Defect Repair In Vivo in Normal and Osteoporotic Rats

Table 1

3D microarchitectural properties (mean ± SD) of cortical bone in osteoporosis induction period.

	Cortical porosity (%)	Bone surface density (mm^−1)	Bone surface-to-volume ratio (mm^−1)	Pore size (m)	Cortical thickness (m)
D −90 ()	2.4 ± 1	5.48 ± 0.53	5.62 ± 0.54	0.03 ± 0.004	0.28 ± 0.02
D −7 ()	2.9 ± 1	4.15 ± 0.51	4.37 ± 0.52	0.04 ± 0.008	0.32 ± 0.02
D0 ()	2.8 ± 1	5.41 ± 0.7	5.69 ± 0.72	0.05 ± 0.02	0.28 ± 0.03
ANOVA	P = 0.1794	P < 0.001	P < 0.001	P = 0.002	P < 0.001
Difference between groups	NS	D −7 < D −90, D0	D −7 < D −90, D0	D −90 < D −7 < D0	D −7 > D −90, D0

D0 = day 0, D −7 = day −7, and D −90 = day −90 before bone surgery. Values are expressed as mean for group, measured on both hind legs ± standard deviation. NS = no significance. values < 0.05 are considered significant.