Research Article

Candida Bloodstream Infections in Italy: Changing Epidemiology during 16 Years of Surveillance

Table 3

Risk analysis of death with a univariate logistic mode.

Death
Living
(Wald test)

Age, years (median, I and III quartile)58.0 (44.0–74.0)42.0 (8.0–64.0)<0.0001
Gender, (%)
 Male72 (64.9)187 (66.1)0.819
 Female39 (35.1)96 (33.9)
Catheter, . (%)
 Yes99 (89.2)241 (85.2)0.128
 No12 (10.8)42 (14.8)
Antibiotic therapy, . (%)
 Yes97 (87.4) 245 (86.6)0.830
 No14 (12.6)38 (13.4)
Antifungal prophylaxis, . (%)
 Yes36 (32.4)87 (30.7)0.745
 No 75 (67.6)196 (69.3)
Candida species, . (%)
C. albicans 48 (43.2)126 (44.5)0.001
C. parapsilosis 24 (21.6)113 (9.9)
C. glabrata 11 (9.9)11 (3.9)
C. guilliermondii 7 (6.3)12 (4.2)
C. tropicalis 8 (7.2)11 (3.9)
C. krusei 6 (5.4)5 (1.8)
 Other7 (6.3)5 (1.8)
Department, . (%)
 Adult oncohaematology5 (4.5)18 (6.4)<0.001
 Pediatric oncohaematology49 (17.3)
 NICU12 (10.8)54 (19.1)
 ICU58 (52.2)65 (23)
 General surgery12 (10.8)45 (15.9)
 General internal medicine17 (15.3)43 (15.2)
 Specialist surgery7 (6.3)8 (2.8)

NICU: neonatal intensive care unit.
ICU: intensive care unit.
Wilcoxon test.
The pediatric haematology patients were excluded from analysis because none of the candidemic patients died.