Neuroprotection in Preterm Infants

Table 2

Neuroprotection by delayed clamping of the umbilical cord.

	ICC (), (%)	DCC (), (%)		Odds ratio	95% CI
IVH
Total	13 (36)	5 (14)	0.03	3.5	1.1–11
Grade 1	4 (11)	3 (8)
Grade 2	8 (22)	2 (6)
Grade 4	1 (3)	0 (0)
Sepsis	8 (22)	1 (3)	0.03	0.1	0.01–0.84

Among infants born before the 32nd week of pregnancy, delayed clamping of the umbilical cord (DCC: delayed cord clamping 30–45 s) reduced the rate of intraventricular brain hemorrhage (IHV) and neonatal sepsis significantly when compared to immediate severance of the cord (ICC: immediate cord clamping 5–10 s) [94].