Analysis of the Expression and Polymorphism of APOE, HSP, BDNF, and GRIN2B Genes Associated with the Neurodegeneration Process in the Pathogenesis of Primary Open Angle Glaucoma

Table 1

The clinical parameters characteristic of open angle glaucoma (POAG) patients and control groups.

	Parameters	Patient groups	Control groups
Number	Gender; (male/female)	98/265	174/232
	Hypertension	218	132
	Low blood pressure	75	54
	Vascular disease	124	92
	Diabetes mellitus type 2	70	104
Mean ± SD	Age (years)	73 ± 10	64 ± 16
	Intraocular pressure, IOP (mmHg)	12.82 ± 2.9	11.9 ± 1.9
	Cup disk ratio (c/d); right eye/left eye	0.74 ± 0.15/0.74 ± 0.27	PNM
	Rim area (RA); right eye/left eye	1.45 ± 3.57/1.29 ± 1.07	PNM
	Retinal nerve fiber layer (RNFL); right eye/left eye	0.39 ± 3.25/0.94 ± 12.13	PNM
	Nerve fiber index (NRI); right eye/left eye	32.47 ± 19.57/25.92 ± 17.11	PNM

Systolic pressure >140; diastolic pressure >90 mmHg.
Systolic pressure <90; diastolic pressure <60 mmHg.
PNM: parameter not measured.