A MicroRNA-Transcription Factor Blueprint for Early Atrial Arrhythmogenic Remodeling

Table 1

The miRNAs significantly up- or downregulated in the paced LA, ordered by the fold change (FC).

miRNA	FC	Direction	value	Reported expression in^∗	Reference
ssc-miR-7140-3p	3,92	Up	0,0199	Porcine lung	[25]
ssc-miR-4335	3,22	Up	0,0540	Porcine intestine	[26]
ssc-miR-129b	2,90	Up	0,0520	Catfish heart	[27]
ssc-miR-296-5p	2,35	Up	0,0530	Human placenta	[28]
ssc-miR-4334-5p	2,22	Up	0,0072	Porcine intestine	[26]
ssc-miR-4339	2,16	Up	0,0499	Porcine intestine	[26]
ssc-miR-182	2,13	Up	0,0021	Human skeletal muscles	[29]
ssc-miR-4332	1,95	Up	0,0339	Porcine intestine	[26]
ssc-miR-1249	1,90	Up	0,0550	Rat pancreas	[30]
ssc-miR-1307	1,83	Up	0,0542	Human blood cells	[31]
ssc-miR-671-3p	1,63	Up	0,0492	Human atria	[23]
ssc-miR-423-3p	1,61	Up	0,0025	Rat hippocampus	[32]
ssc-miR-23b	−1,10	Down	0,0146	Human atria, AF	[20]
ssc-miR-22-3p	−1,19	Down	0,0181	Human atria, AF	[20]
ssc-miR-143-3p	−1,26	Down	0,0402	Human atria, AF	[20]
ssc-miR-324	−1,30	Down	0,0050	Human blood cells	[33]
ssc-miR-455-5p	−1,42	Down	0,0551	Human meningeal arteries	[34]
ssc-miR-326	−1,46	Down	0,0546	Human brain tissues	[35]
ssc-miR-362	−1,57	Down	0,0069	Human skeletal muscles	[36]
ssc-miR-363	−1,62	Down	0,0069	Human atria, AF	[21]
ssc-miR-18b	−1,67	Down	0,0550	Human atria, AF	[21]
ssc-miR-17-3p	−1,68	Down	0,0336	Mouse heart	[37]
ssc-miR-24-2-5p	−1,79	Down	0,0187	Human atria, AF	[23]
ssc-miR-542-5p	−1,85	Down	0,0318	Human atria, AF	[23]
ssc-miR-486	−1,88	Down	0,0365	Mouse skeletal muscles	[38]
ssc-miR-27b-5p	−1,96	Down	0,0509	Human atria, AF	[23]
ssc-miR-7	−2,37	Down	0,0211	Porcine heart	[39]
ssc-miR-30c-3p	−2,55	Down	0,0345	Porcine heart	[39]
ssc-miR-381	−2,69	Down	0,0540	Human skeletal muscles	[40]

^∗Except the expression in malignant tumors and model cell lines. Bold, detected in AF patient samples.