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BioMed Research International

BioMed Research International / 2015 / Article / Tab 1

Research Article

Iron Dextran Increases Hepatic Oxidative Stress and Alters Expression of Genes Related to Lipid Metabolism Contributing to Hyperlipidaemia in Murine Model

Table 1

Iron status in liver, glycemic and lipids profile, oxidant/antioxidant status in liver of rats offered a standard diet (S) and rats that received injections of iron dextran (SI).
 S group SI group values
Liver iron µmol/100 mg tissue0.02 ± 0.01 0.18 ± 0.05*<0.0001
Cholesterol mmol/L of serum 1.26 ± 0.271.77 ± 0.33*<0.05
HDL cholesterol mmol/L of serum 0.83 ± 0.170.93 ± 0.17>0.05
Other fraction cholesterol mmol/L of serum0.42 ± 0.280.84 ± 0.37*<0.05
Triacylglycerol mmol/L of serum 1.15 ± 0.222.06 ± 0.59*<0.01
Glucose mmol/L of serum 6.24 ± 0.967.34 ± 0.46*<0.05
ALT (U/mL of serum) 23.72 ± 4.3425.68 ± 7.32>0.05
AST (U/mL of serum) 55.26 ± 4.2656.92 ± 3.61>0.05
Liver carbonyl protein (U/mg of protein) 2.95 ± 0.56.83 ± 1.86*<0.0001
Liver TBARS (U/mg of protein) 1.47 ± 0.233.21 ± 0.38*<0.0001
HDL, high-density lipoprotein;
Values are shown as the mean ± standard deviation (). Data were analyzed by -test. Statistical differences are shown by *.