Research Article

Characterization of Closed Head Impact Injury in Rat

Table 2

Assignment of six factors and their selected levels in the L8(27) orthogonal array and predicted peak maximum principal strain (MPS) in the cerebrum, hippocampus, and cerebellum.

Case numberFactorsPredicted peak MPS
ABCDEFCerebrumHippocampusCerebellum

113Central6SteelFlat0.17750.14660.1535
213Lateral6NylonConvex0.22830.15930.0326
316Central12SteelConvex0.20610.09120.0494
416Lateral12NylonFlat0.40800.29930.1261
523Central12NylonFlat0.61920.36440.3890
623Lateral12SteelConvex0.37440.30800.1238
726Central6NylonConvex0.30470.22040.1976
826Lateral6SteelFlat0.49820.40920.2893

A (impact depth, mm), B (impact velocity, m/s), C (impact position), D (impactor diameter, mm), E (impactor material), and F (impactor shape).