Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2015, Article ID 279192, 8 pages
http://dx.doi.org/10.1155/2015/279192
Research Article

Short Duration Combined Mild Hypothermia Improves Resuscitation Outcomes in a Porcine Model of Prolonged Cardiac Arrest

1Emergency Department, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
2Institute of Cardiopulmonary Cerebral Resuscitation, Sun Yat-sen University, Guangzhou 510120, China
3Emergency Department, Affiliated Dongguan Hospital, Medical College of Jinan University, Dongguan 523900, China
4Biomedical Engineering Department, Guangzhou Medical University, Guangzhou 511436, China
5School of Biomedical Engineering, Third Military Medical University, Chongqing 400038, China

Received 22 May 2015; Revised 24 August 2015; Accepted 21 September 2015

Academic Editor: Clifton W. Callaway

Copyright © 2015 Tao Yu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Hollenberg, J. Herlitz, J. Lindqvist et al., “Improved survival after out-of-hospital cardiac arrest is associated with an increase in proportion of emergency crew-witnessed cases and bystander cardiopulmonary resuscitation,” Circulation, vol. 118, no. 4, pp. 389–396, 2008. View at Publisher · View at Google Scholar · View at Scopus
  2. W. Hua, L.-F. Zhang, Y.-F. Wu et al., “Incidence of sudden cardiac death in China: analysis of 4 regional populations,” Journal of the American College of Cardiology, vol. 54, no. 12, pp. 1110–1118, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. Hypothermia after Cardiac Arrest Study Group, “Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest,” The New England Journal of Medicine, vol. 346, no. 22, pp. 549–556, 2002. View at Publisher · View at Google Scholar
  4. S. A. Bernard, T. W. Gray, M. D. Buist et al., “Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia,” The New England Journal of Medicine, vol. 346, no. 8, pp. 557–563, 2002. View at Publisher · View at Google Scholar · View at Scopus
  5. R. A. Berg, R. Hemphill, B. S. Abella et al., “Part 5: adult basic life support: 2010 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care,” Circulation, vol. 122, no. 3, pp. S685–S705, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. R. W. Koster, M. R. Sayre, M. Botha et al., “Part 5: adult basic life support: 2010 International consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations,” Resuscitation, vol. 81, supplement 1, pp. e48–e70, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. S. Scolletta, F. S. Taccone, P. Nordberg, K. Donadello, J.-L. Vincent, and M. Castren, “Intra-arrest hypothermia during cardiac arrest: a systematic review,” Critical Care, vol. 16, no. 2, article R41, 2012. View at Publisher · View at Google Scholar · View at Scopus
  8. T. Yu, D. Barbut, G. Ristagno et al., “Survival and neurological outcomes after nasopharyngeal cooling or peripheral vein cold saline infusion initiated during cardiopulmonary resuscitation in a porcine model of prolonged cardiac arrest,” Critical Care Medicine, vol. 38, no. 3, pp. 916–921, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. V. Yajnik and H. Gomez, “Prehospital induction of mild hypothermia with cold normal saline for cardiac arrest: more harm than good?” Critical Care, vol. 18, no. 5, article 559, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. D. Yannopoulos, M. Zviman, V. Castro et al., “Intra-cardiopulmonary resuscitation hypothermia with and without volume loading in an ischemic model of cardiac arrest,” Circulation, vol. 120, no. 14, pp. 1426–1435, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. F. Kim, G. Nichol, C. Maynard et al., “Effect of prehospital induction of mild hypothermia on survival and neurological status among adults with cardiac arrest a randomized clinical trial,” The Journal of the American Medical Association, vol. 311, no. 1, pp. 45–52, 2014. View at Publisher · View at Google Scholar · View at Scopus
  12. H. Soleimanpour, F. Rahmani, S. E. Golzari et al., “Main complications of mild induced hypothermia after cardiac arrest: a review article,” Journal of Cardiovascular and Thoracic Research, vol. 6, no. 1, pp. 1–8, 2014. View at Google Scholar
  13. S. Ye, Y. Weng, S. Sun et al., “Comparison of the durations of mild therapeutic hypothermia on outcome after cardiopulmonary resuscitation in the rat,” Circulation, vol. 125, no. 1, pp. 123–129, 2012. View at Publisher · View at Google Scholar · View at Scopus
  14. H. Li, L. Zhang, Z. Yang et al., “Even four minutes of poor quality of CPR compromises outcome in a porcine model of prolonged cardiac arrest,” BioMed Research International, vol. 2013, Article ID 171862, 6 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  15. F. Colbourne and D. Corbett, “Delayed postischemic hypothermia: a six month survival study using behavioral and histological assessments of neuroprotection,” The Journal of Neuroscience, vol. 15, no. 11, pp. 7250–7260, 1995. View at Google Scholar · View at Scopus
  16. B. S. Abella, D. Zhao, J. Alvarado, K. Hamann, T. L. Vanden Hoek, and L. B. Becker, “Intra-arrest cooling improves outcomes in a murine cardiac arrest model,” Circulation, vol. 109, no. 22, pp. 2786–2791, 2004. View at Publisher · View at Google Scholar · View at Scopus
  17. M. Carroll and O. Beek, “Protection against hippocampal CA1 cell loss by post-ischemic hypothermia is dependent on delay of initiation and duration,” Metabolic Brain Disease, vol. 7, no. 1, pp. 45–50, 1992. View at Publisher · View at Google Scholar · View at Scopus
  18. J. Bro-Jeppesen, J. Kjaergaard, H. Søholm et al., “Hemodynamics and vasopressor support in therapeutic hypothermia after cardiac arrest: prognostic implications,” Resuscitation, vol. 85, no. 5, pp. 664–670, 2014. View at Publisher · View at Google Scholar · View at Scopus
  19. X. Yue, H. Mehmet, J. Penrice et al., “Apoptosis and necrosis in the newborn piglet brain following transient cerebral hypoxia-ischaemia,” Neuropathology and Applied Neurobiology, vol. 23, no. 1, pp. 16–25, 1997. View at Publisher · View at Google Scholar · View at Scopus
  20. P. Teschendorf, S. A. Padosch, F. Spöhr et al., “Time course of caspase activation in selectively vulnerable brain areas following global cerebral ischemia due to cardiac arrest in rats,” Neuroscience Letters, vol. 448, no. 2, pp. 194–199, 2008. View at Publisher · View at Google Scholar · View at Scopus
  21. F. Colbourne, H. Li, and A. M. Buchan, “Continuing postischemic neuronal death in CA1: influence of ischemia duration and cytoprotective doses of NBQX and SNX-111 in rats,” Stroke, vol. 30, no. 3, pp. 662–668, 1999. View at Publisher · View at Google Scholar · View at Scopus
  22. M. Horn and W. Schlote, “Delayed neuronal death and delayed neuronal recovery in the human brain following global ischemia,” Acta Neuropathologica, vol. 85, no. 1, pp. 79–87, 1992. View at Publisher · View at Google Scholar · View at Scopus
  23. J. Guan, D. Barbut, H. Wang et al., “A comparison between head cooling begun during cardiopulmonary resuscitation and surface cooling after resuscitation in a pig model of cardiac arrest,” Critical Care Medicine, vol. 36, no. 11, supplement, pp. S428–S433, 2008. View at Publisher · View at Google Scholar · View at Scopus
  24. X. Lu, L. Ma, S. Sun, J. Xu, C. Zhu, and W. Tang, “The effects of the rate of postresuscitation rewarming following hypothermia on outcomes of cardiopulmonary resuscitation in a rat model,” Critical Care Medicine, vol. 42, no. 2, pp. e106–e113, 2014. View at Publisher · View at Google Scholar · View at Scopus
  25. A. Bouwes, L. B. M. Robillard, J. M. Binnekade et al., “The influence of rewarming after therapeutic hypothermia on outcome after cardiac arrest,” Resuscitation, vol. 83, no. 8, pp. 996–1000, 2012. View at Publisher · View at Google Scholar · View at Scopus