Research Article

Cinnabar Induces Renal Inflammation and Fibrogenesis in Rats

Table 2

Urinary KIM-1, but not SCr, increased in cinnabar-treated rats.

Group8 weeks12 weeks
KIM-1 (ng/g)SCr (μmol/L)KIM-1 (ng/L)SCr (μmol/L)

Control696.97 ± 7.0726.22 ± 5.7299.41 ± 6.77 28.45 ± 6.20
Cinnabar6114.02 ± 11.56*25.93 ± 6.68120.62 ± 11.86**30.27 ± 5.66

KIM-1: kidney injury molecule-1. SCr: serum creatinine. Results represent mean ± SE of six animals per group. , , compared with the control group.