The Combinational Polymorphisms of ORAI1 Gene Are Associated with Preventive Models of Breast Cancer in the Taiwanese
Table 2
The top ten best protective association models of 2-SNP combinations.
Specific 2-SNP combination*1
Genotypes*1
Case number /control number
OR
95% CI
value
Power
1-2
Others
330/261
1
0.005*2
0.792
1-1
15/29
0.409
0.215–0.779
2-4
Others
330/261
1
0.010*2
0.752
1-1
15/28
0.424
0.222–0.810
1-3
Others
278/219
1
0.123
0.339
1-2
67/71
0.743
0.509–1.085
2-3
Others
327/261
1
0.022*2
0.629
1-2
18/29
0.495
0.269–0.912
1-4
Others
310/247
1
0.073
0.432
1-1
35/43
0.649
0.403–1.044
3-4
Others
310/247
1
0.073
0.432
2-1
35/43
0.649
0.403–1.044
4-5
Others
311/249
1
0.096
0.385
1-2
34/41
0.664
0.409–1.078
2-5
Others
325/261
1
0.048*2
0.506
1-2
20/29
0.554
0.306–1.002
1-5
Others
289/234
1
0.311
0.174
1-2
56/56
0.810
0.538–1.218
2-3
Others
292/239
1
0.451
0.118
2-1
53/51
0.851
0.558–1.296
The information of the SNP and genotypes is provided in Table 1. *2The models have significance on the occurrence of breast cancer ( < 0.05). OR = odds ratio.
