Muscle IGF-1-Induced Skeletal Muscle Hypertrophy Evokes Higher Insulin Sensitivity and Carbohydrate Use as Preferential Energy Substrate

Figure 1

(a) Wet weight of EDL and soleus muscles from WT (open bars) and MLC/mIGF-1 mice (filled bars). (b) Composition of each fiber type in EDL (type I, IIa/IId and IIb) and soleus (type I, IC/IIC and IIa) muscles from WT (open bars) and MLC/mIGF-1 mice (filled bars). (c) Cross-sectional area-CSA (μm²) of each fiber type in EDL and soleus muscles from WT (open bars) and MLC/mIGF-1 (filled bars) mice. (d) Serial cross-sections of the EDL and soleus muscles from WT and MLC/mIGF-1 mice muscle were submitted to histochemistry mATPase at pH 4.1 and 10.3. Data expressed as mean ± SEM. -5; versus WT muscles.

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