Research Article
Antimicrobial Effects and Resistant Regulation of Magnolol and Honokiol on Methicillin-Resistant Staphylococcus aureus
Table 1
Antibacterial activity tests of magnolol against methicillin-resistant S. aureus (MRSA).
| | S. aureus strain | Class | Magnolol (g/mL | Oxacillin 25 g/mL +
magnolol (g/mL | | 0 | 1 | 10 | 25 | 50 | 0 | 1 | 10 | 25 | 50 |
| | ATCC25923 | MSSA | +++ | +++ | +++ | +/− | — | — | — | — | — | — | | ATCC33591 | MRSA | +++ | +++ | +++ | +/− | — | +++ | +++ | +++ | — | — | | Clinical isolates | | | | | | | | | | | | | S. aureus 78 | MRSA | +++ | +++ | +++ | — | — | +++ | +++ | — | — | — | | S. aureus M11 | MRSA | +++ | +++ | +++ | +/− | — | +++ | +++ | — | — | — | | S. aureus 21-8 | MRSA | +++ | +++ | +++ | — | — | +++ | +++ | +/− | — | — | | S. aureus 6-2 | MRSA | +++ | +++ | +++ | — | — | +++ | +++ | — | — | — | | S. aureus 7-3 | MRSA | +++ | +++ | +++ | +/− | — | +++ | +++ | — | — | — | | S. aureus 8-4-1 | MRSA | +++ | +++ | +++ | +/− | — | +++ | +++ | — | — | — | | S. aureus 8-4-2 | MRSA | +++ | +++ | +++ | +/− | — | +++ | +++ | — | — | — | | S. aureus 9-5 | MRSA | +++ | +++ | +++ | +/− | — | +++ | +++ | — | — | — | | S. aureus 13-7 | MRSA | +++ | +++ | +++ | — | — | +++ | +++ | +/− | — | — | | S. aureus 27-9 | MRSA | +++ | +++ | +++ | — | — | +++ | +++ | — | — | — | | S. aureus 47-10 | MRSA | +++ | +++ | +++ | — | — | +/− | +/− | — | — | — | | S. aureus 105-13 | MRSA | +++ | +++ | +++ | +/− | — | +++ | +++ | — | — | — | | S. aureus 106-14 | MRSA | +++ | +++ | +++ | +/− | — | +++ | +++ | +/− | — | — |
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+++: growing very well; +/−: growing slightly; —: no growth.
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