Table 2: Organ/tissue concentration and biodistribution of 68Ga-DOTA-TBIA101 in Escherichia coli infected mice.

Organ/tissue Activity concentration
(SUV)
Compound distribution
(%ID)
InfectedHealthy control*InfectedHealthy control

Heart16 ± 2.20.439.58.9
Lung0.73 ± 0.030.480.500.50
Liver25 ± 3.9141414
Kidneys59 ± 6.3353636
Brain0.90 ± 0.10.550.550.57
Intestine0.90 ± 0.10.540.580.57
Urinary tract/bladder34 ± 2.9202121
Forearm muscle1.1 ± 0.20.580.630.60
Hind muscle (CL)1.5 ± 0.30.730.770.76
Hind muscle (E.coli)1.7 ± 0.30.730.940.76
Hind muscle (CL) to forearm muscle1.4 ± 0.1NANANA
Hind muscle (E.coli) to background ratio2.3 ± 0.5NANANA
Hind muscle (E.coli) to forearm muscle1.6 ± 0.1NANANA
Hind muscle (E.coli) hind muscle (CL)1.2 ± 0.1NANANA

Values expressed as mean ± SEM. E.coli = Escherichia coli 22952 , healthy control , and CL = contralateral. *The SUV values were calculated from the same region of interest area using one healthy animal.