Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2015, Article ID 285491, 14 pages
http://dx.doi.org/10.1155/2015/285491
Research Article

The 482Ser of PPARGC1A and 12Pro of PPARG2 Alleles Are Associated with Reduction of Metabolic Risk Factors Even Obesity in a Mexican-Mestizo Population

1Instituto de Investigación en Reumatología y del Sistema Musculo Esquelético, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Sierra Mojada No. 950, Colonia Independencia, 44340 Guadalajara, JAL, Mexico
2Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Sierra Mojada No. 950, Colonia Independencia, 44340 Guadalajara, JAL, Mexico
3Servicio de Reumatología, Hospital Civil “Dr. Juan I. Menchaca”, Salvador Quevedo y Zubieta No. 750, Colonia Independencia, 44340 Guadalajara, JAL, Mexico
4UDG-CA-701, Grupo de Investigación Inmunometabolismo en Enfermedades Emergentes (GIIEE), Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Sierra Mojada No. 950, Colonia Independencia, 44340 Guadalajara, JAL, Mexico
5Tecnológico de Monterrey, Campus Guadalajara, Avenida General Ramón Corona No. 2514, Colonia Nuevo México, 45201 Zapopan, JAL, Mexico
6Departamento de Farmacobiología, Centro Universitario de Ciencias Exactas e Ingenierías, Universidad de Guadalajara, Boulevard Marcelino García Barragán 1421, 44430 Guadalajara, JAL, Mexico
7HMIELM, Secretaria de Salud Jalisco, Avenida Constituyentes 1075, Colonia Moderna, 44190 Guadalajara, JAL, Mexico

Received 1 September 2014; Revised 19 November 2014; Accepted 23 November 2014

Academic Editor: Tiziano Verri

Copyright © 2015 Mónica Vázquez-Del Mercado et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [7 citations]

The following is the list of published articles that have cited the current article.

  • Xianyin Lai, Christopher B. Umbricht, Kurt Fisher, Justin Bishop, Qiuying Shi, and Shaoxiong Chen, “Identification of novel biomarker and therapeutic target candidates for diagnosis and treatment of follicular carcinoma,” Journal of Proteomics, 2017. View at Publisher · View at Google Scholar
  • Roxanne Vandenbeek, Naveen P Khan, and Jennifer L Estall, “Linking Metabolic Disease With the PGC-1α Gly482Ser Polymorphism,” Endocrinology, vol. 159, no. 2, pp. 853–865, 2017. View at Publisher · View at Google Scholar
  • Becer, and Çlrakoǧlu, “Effect of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor γ2 gene on lipid profile and adipokines levels in obese subjects,” Balkan Journal of Medical Genetics, vol. 20, no. 1, pp. 71–79, 2017. View at Publisher · View at Google Scholar
  • Vitai, Korányi, Csép, and Szigeti, “The ppargc1a - Gly482Ser polymorphism (RS8192678) and the metabolic syndrome in a central romanian population,” Acta Endocrinologica, vol. 13, no. 2, pp. 161–167, 2017. View at Publisher · View at Google Scholar
  • Paula Costa-Urrutia, Carolina Abud, Valentina Franco-Trecu, Valentina Colistro, Martha Eunice Rodríguez-Arellano, Julio Granados, and Marilia Seelaender, “Genetic susceptibility to pre diabetes mellitus and related association with obesity and physical fitness components in Mexican-Mestizos,” Primary Care Diabetes, 2018. View at Publisher · View at Google Scholar
  • Josefina Aguayo-Armendáriz, Maricela Montalvo-Corral, Karla A. González-Martínez, María I. Grijalva-Haro, Martha N. Ballesteros-Vásquez, Graciela Caire-Juvera, and Silvia Y. Moya-Camarena, “Central obesity and body fat, but not BMI, are associated with the Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma gene in a population with a high consumption of saturated and trans fatty acids9,” Nutrition Research, 2018. View at Publisher · View at Google Scholar
  • Armando Totomoch-Serra, Maria De Lourdes Munoz, Juan Burgueno, Maria Cristina Revilla-Monsalve, and Alvaro Diaz-Badillo, “Association of common polymorphisms in the VEGFA and SIRT1 genes with type 2 diabetes-related traits in Mexicans,” Archives of Medical Science, vol. 14, no. 6, pp. 1361–1373, 2018. View at Publisher · View at Google Scholar