BioMed Research International

Research Article

The 482Ser of PPARGC1A and 12Pro of PPARG2 Alleles Are Associated with Reduction of Metabolic Risk Factors Even Obesity in a Mexican-Mestizo Population

Table 2

Correlations of metabolic markers profile with body adiposity measurements.


Measurements	Glucose	Insulin	HOMA-IR	Triglycerides	Total cholesterol	HDLc	LDLc	VLDLc	Apo A-1	Apo B
Measurements	⁺Correlation,

Body weight (kg)	0.270^**	0.335^**	0.353^**	0.313^**	0.215^**	−0.082	0.116^*	0.308^**	−0.113	0.346^**
Body weight (kg)	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001	0.114	0.026	<0.0001	0.175	<0.0001

BMI (kg/m²)	0.380^**	0.397^**	0.435^**	0.350^**	0.322^**	−0.033	0.195^**	0.344^**	−0.018	0.345^**
BMI (kg/m²)	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001	0.526	<0.0001	<0.0001	0.826	<0.0001

Total body fat mass (kg)	0.339^**	0.324^**	0.366^**	0.284^**	0.284^**	0.058	0.173^**	0.284^**	0.026	0.317^**
Total body fat mass (kg)	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001	0.322	0.003	<0.0001	0.834	0.006

Body fat ratio	0.362^**	0.409^**	0.443^**	0.336^**	0.309^**	−0.028	0.191^**	0.330^**	−0.021	0.343^**
Body fat ratio	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001	0.590	<0.0001	<0.0001	0.801	<0.0001

Waist circumference (cm)	0.325^**	0.271^**	0.305^**	0.401^**	0.375^**	−0.124^*	0.268^**	0.396^**	−0.182^*	0.467^**
Waist circumference (cm)	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001	0.026	<0.0001	<0.0001	0.041	<0.0001

Hip circumference (cm)	0.224^**	0.293^**	0.305^**	0.177^**	0.243^**	0.042	0.146^**	0.165^**	0.011	0.200^*
Hip circumference (cm)	<0.0001	<0.0001	<0.0001	0.001	<0.0001	0.455	0.009	0.003	0.903	0.021

WHR	0.325^**	0.271^**	0.305^**	0.401^**	0.375^**	−0.124^*	0.268^**	0.396^**	−0.182^*	0.467^**
WHR	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001	0.026	<0.0001	<0.0001	0.041	<0.0001

Conicity index	0.259^**	0.092	0.128^*	0.368^**	0.360^**	−0.156^**	0.281^**	0.366^**	−0.256^**	0.462^**
Conicity index	<0.0001	0.099	0.022	<0.0001	<0.0001	0.005	<0.0001	<0.0001	0.004	<0.0001

Total adipose area (cm²)	0.325^**	0.271^**	0.305^**	0.401^**	0.375^**	−0.124^*	0.268^**	0.396^**	−0.182^*	0.467^**
Total adipose area (cm²)	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001	0.026	<0.0001	<0.0001	0.041	<0.0001

Abdominal volume index (L)	0.324^**	0.275^**	0.308^**	0.394^**	0.373^**	−0.117^*	0.266^**	0.390^**	−0.176^*	0.463^**
Abdominal volume index (L)	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001	0.035	<0.0001	<0.0001	0.049	<0.0001

HOMA-IR: homeostasis model assessment-insulin resistance; Glucose, HDLc, LDLc, and VLDLc: high, low, and very low density lipoprotein cholesterol, respectively; Apo: apolipoprotein mg/dL. Insulin, μIU/mL. ^**Significant correlation at 0.01 level. ^*Significant correlation at 0.05 level. ⁺ Pearson/Rho of Spearman correlations test.