Methylglyoxal Induced Basophilic Spindle Cells with Podoplanin at the Surface of Peritoneum in Rat Peritoneal Dialysis Model

Table 1

Pathological findings of the peritoneum in peritoneal injury rats.

	MGO	FA	CG	Talc
Loss of monolayer of mesothelial cells	+++	+++	+++	−
Appearance of basophilic spindle cells	++	−	−	−
Phagocytosis in macrophages	−	−	+−	++
Foreign body inflammation	−	−	−	++
Edema	−	−	+	−
Mononuclear cell infiltration	++	+	++	++
Neovascularization	++	+	+	+
Fibrosis	+	+	+	+

MGO: methylglyoxal-treated rats, FA: formaldehyde-treated rats, CG: chlorhexidine gluconate-treated rats, and talc: talc-treated rats.
+: mild, ++: moderate, and +++: severe.