The Quantified Level of Circulating Prostate Stem Cell Antigen mRNA relative to GAPDH Level Is a Clinically Significant Indictor for Predicting Biochemical Recurrence in Prostate Cancer Patients after Radical Prostatectomy

Table 3

Multivariate analysis of BCR-related risk factors using stratified PSCA/GAPDH ratio into three subgroups.

	value	Hazard ratio	95.0% confidence interval
			Lower limit	Upper limit
Lymphovascular invasion	0.072	0.059	0.003	1.293
Perineural invasion	0.721	0.612	0.042	9.024
Extraprostatic capsule extension	0.008	0.006	0.001	0.271
Seminal vesicle invasion	0.589	1.464	0.367	5.838
Lymph node dissection	0.048	16.437	1.024	263.859
Resection margin negative	0.002	27.453	3.500	215.318
Neurovascular saving	0.110	4.217	0.723	24.603
Clinical T1	0.006
cT2a, T2b	0.165	0.077	0.002	2.864
cT2c	0.013	0.104	0.018	0.621
≥cT3	0.083	14.700	0.706	306.063
Pathologic Gleason score	0.801	1.256	0.213	7.397
PSCA/GAPDH >1.5	0.052
1.0–1.5	0.016	12.722	1.598	101.286
<1.0	0.135	5.403	0.590	49.499
Preoperative PSA	0.004	1.225	1.068	1.406
Pathologic ≤T2b	0.494	0.403	0.030	5.468