Research Article

Chewing Prevents Stress-Induced Hippocampal LTD Formation and Anxiety-Related Behaviors: A Possible Role of the Dopaminergic System

Figure 1

Effects of acute stress and SCH23390 on hippocampal CA1 LTD. (a) Time course of mean fEPSP slopes for different experimental groups. CT, ST, and SC refer to rats in the control, stressed, and stressed-with-chewing groups, respectively, without SCH23390 administration. LFS was applied during 20–35 min to induce LTD. (b) Time course of mean fEPSP slopes for SCH23390-treated SC groups (SC+SCH23390). Data from groups ST and SC were taken from (a) and superimposed for the comparison.
(a)
(b)