Inverse Association between Prediagnostic IgE Levels and the Risk of Brain Tumors: A Systematic Review and Meta-Analysis

Table 2

Summary of meta-analysis results.

Comparisons	Number of studies	^aRR [95% CI]	value	Tests for heterogeneity
				(%)
Total IgE level
Brain tumors	6	0.73 [0.61–0.86]	<0.001	39.5	0.142
Men	2	0.83 [0.63–1.10]	0.202	0.0	0.602
Women	2	0.69 [0.43–1.11]	0.125	0.0	0.450
Glioma	5	0.74 [0.62–0.88]	0.001	50.6	0.088
Men	2	0.83 [0.63–1.10]	0.202	0.0	0.602
Women	2	0.69 [0.43–1.11]	0.125	0.0	0.450
Respiratory allergen-specific IgE level
Brain tumors	6	0.88 [0.77–1.00]	0.055	0.0	0.527
Men	4	0.96 [0.78–1.19]	0.744	0.0	0.770
Women	4	0.87 [0.67–1.15]	0.331	51.6	0.103
Glioma	5	0.87 [0.76–1.00]	0.051	0.0	0.407
Men	3	0.99 [0.80–1.23]	0.923	0.0	0.878
Women	3	0.81 [0.59–1.10]	0.172	60.3	0.081

: relative risk; 95% CI: 95% confidence interval; : P values for pooled analysis; : values for heterogeneity analysis.