The Prognosis of IVF in Poor Responders Depending on the Bologna Criteria: A Large Sample Retrospective Study from China
Table 4
The basic characteristics and clinical outcomes of subgroup patients diagnosed by Bologna criteria.
All criteria
Age + oocyte
Age + AFC
Oocyte + AFC
1772
404
1410
2184
—
AGE (yr)
41.0 ± 4.2
41.3 ± 3.9
42.0 ± 1.8
34.6 ± 3.5
0.000
Duration of infertility (yr)
7.6 ± 6.2
7.4 ± 5.9
8.0 ± 6.0
6.1 ± 4.1
0.000
Primary infertility (%)
36.5 (646/1772)
37.9 (153/404)
29.6 (418/1410)
53.6 (1171/2184)
0.000
BMI (kg/m2)
22.8 ± 3.1
22.7 ± 3.3
23.0 ± 3.0
22.3 ± 3.2
0.000
Basal FSH (mIU/mL)
10.2 ± 5.4
9.5 ± 5.4
10.3 ± 4.3
9.9 ± 5.3
0.035
AFC
3.7 ± 1.7
9.6 ± 2.5
4.7 ± 1.8
4.2 ± 1.8
0.000
on hCG day (pmol/L)
2847.8 ± 2390.5
2836.1 ± 2390.1
7564.1 ± 4899.6
3213.8 ± 2537.7
0.000
Oocytes retrieved
2.7 ± 1.6
4.3 ± 4.3
7.1 ± 3.7
2.9 ± 1.8
0.000
Gn day
10.9 ± 3.7
10.8 ± 4.2
11.3 ± 2.7
11.1 ± 3.5
0.000
Gn dose (IU)
3821.3 ± 2031.4
3771.1 ± 2016.6
4293.4 ± 1517.6
3862.0 ± 1873.8
0.002
ICSI (%)
33.1 (587/1772)
35.4 (143/404)
40.1 (565/1401)
31.5 (687/2184)
0.000
MII (%)
85.5 (1088/1272)
83.5 (256/310)
79.5 (3406/4282)
85.8 (1343/1565)
0.000
ET
1.5 ± 0.6
1.5 ± 0.6
2.5 ± 0.7
1.5 ± 0.6
0.000
CPR (%)
13.1 (148/1128)
16.0 (40/250)
16.3 (208/1274)
25.7 (369/1438)
0.000
IPR (%)
9.4 (158/1681)
11.9 (45/377)
10.6 (340/3206)
19.4 (423/2180)
0.000
LBR per ET (%)
7.7 (75/974)
6.3 (11/176)
9.2 (111/1209)
17.8 (208/1167)
0.000
LBR per OPU (%)
5.0 (75/1493)
3.8 (11/290)
8.3 (111/1331)
11.7 (208/1772)
0.000
No available oocyte (%)
6.8 (121/1772)
9.4 (38/404)
0
5.8 (126/2184)
0.000
No available embryo (%)
23.5 (416/1772)
22.5 (91/404)
4.5 (63/1410)
23.1 (505/2184)
0.000
Values are % and /total or mean ± SD Significant difference between four groups (). Significant difference between all and age + oocyte (). Significant difference between all and age + AFC (). Significant difference between all and oocyte + AFC (). Significant difference between age + oocyte and AGE + AFC (). Significant difference between age + oocyte and oocyte + AFC (). Significant difference between age + AFC and oocyte + AFC ().
