A Novel Injectable Magnesium/Calcium Sulfate Hemihydrate Composite Cement for Bone Regeneration

Figure 10

Histology photomicrographs after hematoxylin and eosin staining and Masson’s Trichrome staining of the decalcified bone defect sections after implantation. (a) 10% Mg/CSH for 4 weeks, hematoxylin and eosin staining; (b) 10% Mg/CSH for 8 weeks, hematoxylin and eosin staining; (c) 10% Mg/CSH for 16 weeks, hematoxylin and eosin staining; (d) CSH for 4 weeks, Masson’s Trichrome staining; (f) CSH for 8 weeks, Masson’s Trichrome staining; (e) 10% Mg/CSH for 4 weeks, Masson’s Trichrome staining; (g) 10% Mg/CSH for 8 weeks, Masson’s Trichrome staining. Magnification: ×200; scale bar for (a)–(c): 200 μm; scale bar for (d)–(g): 500 μm. Abbreviations and signs used: graft (G), host bone (HB), interface of new bone and host bone (IF), magnesium (Mg), and calcium sulfate hemihydrate (CSH). Black arrows indicated the new trabeculae.

(a)

(b)

(c)

(d)

(e)

(f)

(g)