Association of Polymorphic Variants of miRNA Processing Genes with Larynx Cancer Risk in a Polish Population

Table 2

The odds ratio (OR) of the miRNA processing genes single nucleotide polymorphisms in head and neck cancer patients and healthy controls.

Gene/rs number	Genotype	Controls; number	Patients; number	Odds ratio	0.95 confidence intervals
					(0.95 CI)
					Lower limit	Upper limit
DROSHA
6877842	CC	15	6	Ref.
	CG	79	49	1.5506	0.5638	4.2644	0.392883
	GG	76	73	2.4013	0.8836	6.526	0.078775
DICER1
3742330	AA	63	23	Ref.
	AG	103	100	2.6593	1.5326	4.6144	0.0004
	GG	4	0	NA
13078	AA	10	7	Ref.
	AT	124	46	0.53	0.1904	1.4747	0.17013F
	TT	36	75	2.9762	1.0473	8.4579	0.034697
DGCR8
1640299	GG	16	6	Ref.
	GT	93	47	1.3477	0.4949	3.6696	0.559829
	TT	61	60	2.623	0.9614	7.1562	0.053443
3757	AA	15	4	Ref.
	AG	119	89	2.8046	0.9	8.74	0.065196
	GG	36	29	3.0208	0.9039	10.0951	0.064411
417309	AA	8	13	Ref.
	AG	46	32	0.4281	0.1591	1.1516	0.088032
	GG	116	67	0.3554	0.1401	0.9015	0.024484
RAN
14035	CC	67	73	Ref.
	CT	93	32	0.3158	0.1876	0.5317	<0.0001
	TT	10	5	0.4589	0.1492	1.4115	0.165857
TARBP2
784567	AA	35	7	Ref.
	AG	114	70	3.0702	1.2935	7.2871	0.008335
	GG	21	51	12.1429	4.661	31.6345	<0.0001
XPO5
11077	GG	82	26	Ref.
	GT	44	62	4.4441	2.4723	7.9883	<0.0001
	TT	34	36	3.3394	1.7544	6.3563	0.000183