Dynamic Contrast-Enhanced CT Characterization of Xp11.2 Translocation/TFE3 Gene Fusions versus Papillary Renal Cell Carcinomas

Figure 1

Renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusions in a 22-year-old woman with gross hematuria. (a) Abdominal plain CT scan shows a round well-defined mass of 5.0 cm in size with mixed intensity (around 50 HU) in the right kidney. Note the punctate and circular calcification within and around the lesion. (b) The tumor, which involves both the cortex and medulla, shows heterogeneously moderate enhancement (to around 84 HU) during corticomedullary phase. (c) The tumor continues to be enhanced heterogeneously from corticomedullary phase to nephrographic phase (to around 90 HU). The unenhanced areas within the tumor indicate necrosis.

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