Review Article

Molecular Chaperones of Leishmania: Central Players in Many Stress-Related and -Unrelated Physiological Processes

Figure 3

Relationships inferred from the amino acid sequence similarities existing among the members of human and L. major HSP70 families. The phylogeny was inferred using the neighbor-joining method. The optimal tree with the sum of branch length = 7.43402253 is shown. The evolutionary distances were computed using the Poisson correction method. All positions containing gaps and missing data were eliminated. There were a total of 474 positions in the final dataset. Evolutionary analyses were conducted in MEGA6 [8]. See Table 2 for further details of the protein sequences used for this analysis.