Review Article

Molecular Chaperones of Leishmania: Central Players in Many Stress-Related and -Unrelated Physiological Processes

Table 2

Members of the HSP70 family in L. major and their putative orthologs in humans.

L. major protein1
(GeneDB identifiers)
Human protein2
(UniProt ID)

HSP70 (LmjF.28.2770, LmjF28.2780)Hsp70-1a/HSPA1A (P08107); Hsp70-1t/HSPA1L (P34931); HSPA6 (P17066)

Hsp70-2/HSPA2 (P54652)

Hsc70/HSPA8 (P11142)

BiP or Grp78 (LmjF.28.1200)BiP/HSPA5 (P11021)

HSP70.c (LmjF28.2820)

Hsp70-14 (Q0VDF9)

MtHSP70-1 (LmjF30.2460–2490, LmjF30.2550)MtHSP70/HSPA9 (P38646)

HSP70.4 (LmjF.26.1240)

HSP70.a (LmjF.01.0640)

HSP70.b (LmjF.26.0900)

HSP110 (LmjF.18.1370)Hsp110/HSPA4 (P34932)

HSP110 (LmjF.18.1370)Hsp110-2/HSPA4L (O95757)

HSP110 (LmjF.18.1370)Hsp105/HSPH1 (Q92598)

GRP170 (LmjF.35.4710)Grp170/HSPH4 (B7Z2N4)

Nomenclature according to Folgueira and Requena [15]. GeneDB accession numbers are shown in brackets.
2Nomenclature according to Kampinga and Craig [16]. UniProtKB accession numbers are shown in brackets.