Mycophenolate Mofetil Ameliorates Diabetic Nephropathy in db/db Mice

Figure 1

The effect of MMF on glucose control and diabetic nephropathy of db/db mice. HbA1c and insulin tolerance test (a and b). Kidney injury was observed by PAS staining (original magnification ×400) (c), and the glomerular matrix score was quantified (d). Real-time PCR for TGF-β1, CTGF, and type I and type IV collagen (e). Urinary albumin/creatinine excretion (f). The results are expressed as mean ± SE. , , versus db/m; , versus db/db.

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