A Network Flow Approach to Predict Protein Targets and Flavonoid Backbones to Treat Respiratory Syncytial Virus Infection

Table 2

Prediction of effects of FLA compounds based on chemical structure.

Molecules		H-bond acceptors^*	H-bond donors^*	MV (g/mol)^*	Mutagenic^**	Tumorigenic^**	Irritant^**	Reproductive effect^**
Resveratrol	2.99	3	3	228.247	High-risk	Low-risk	Low-risk	High-risk
Quercetin	1.68	7	5	302.238	High-risk	Medium-risk	Low-risk	Medium-risk
Apigenin	2.46	5	3	270.24	High-risk	Medium-risk	Low-risk	High-risk
Genistein	2.27	5	3	270.24	High-risk	High-risk	Low-risk	High-risk
Myricetin	1.39	8	6	318.237	High-risk	Low-risk	Low-risk	Low-risk
Tricetin	1.68	5	7	302.238	Low-risk	Low-risk	Low-risk	Low-risk

All parameters related to Lipinsky’s rule of five were obtained from Zinc database.
^**All toxicity risks were predicted by Osiris Property Explorer.