PVT1: A Rising Star among Oncogenic Long Noncoding RNAs

Figure 2

The PVT1 locus in humans. (a) UCSC Genome Browser (http://genome.ucsc.edu/) view of the 8q24.21 region in humans, which contains the PVT1 gene. (b) Barplot of cross cancer alteration frequency for the PVT1 gene. -axis: different cancer types from the Cancer Genome Atlas [22]. -axis: total frequency of PVT1 gene alterations. Summary of TCGA cross cancer data and visualization obtained from the cBioPortal for Cancer Genomics (http://www.cbioportal.org/). (c) Sketch of rat and mouse genomic regions syntenic to the human MYC/PVT1 region.

(a)

(b)

(c)