miR-34a and miR-125b Expression in HPV Infection and Cervical Cancer Development

Table 2

Expression profile data for miR-125b and miR-34a in cervical lesions.

	miR-125b			miR-34a
	ΔCt ± sd		-test	ΔCt ± sd		-test
Normal (HPV−) ()	−6.51 ± 1.73	Reference		−0.80 ± 1.16	Reference
Normal (HPV+) ()	−7.59 ± 1.77	2.11 (0.64–7.01)	0.038	−1.56 ± 1.47	1.69 (0.76–3.78)	0.049
LSIL ()	−6.09 ± 1.44	0.75 (0.23–2.48)	0.320	−0.82 ± 1.81	1.01 (0.45–2.27)	0.955
HSIL ()	−5.65 ± 2.15	0.55 (0.17–1.83)	0.099	−0.94 ± 1.59	1.10 (0.49–2.46)	0.707
ICC ()	−4.24 ± 2.10	0.21 (0.06–0.69)	0.004	−1.86 ± 1.56	2.08 (0.93–4.66)	0.042

Ct: cycle threshold; Sd: standard deviation; LSIL: low-grade squamous intraepithelial lesions; HSIL: high-grade squamous intraepithelial lesions; ICC: invasive cervical carcinoma.