Research Article
Effect of Celastrol on Growth Inhibition of Prostate Cancer Cells through the Regulation of hERG Channel In Vitro
Table 1
Effects of Celastrol on cell cycle distribution and early apoptosis (
, ±S).
| Celastrol | Cell cycle (%) | Apoptosis rate (%) | (μmol/L) | G1/G0 | S | G2/M | Sub-G1 |
| 0 (control) | 39.95 ± 1.88 | 49.45 ± 1.67 | 10.60 ± 1.33 | 2.88 ± 0.33 | 0.5 | 40.48 ± 2.34 | 46.19 ± 1.86 | 13.33 ± 1.84 | 1.69 ± 0.24 | 1.0 | 51.40 ± 1.96** | 37.67 ± 2.03** | 10.93 ± 0.98 | 3.25 ± 0.78 | 2.0 | 68.58 ± 2.89** | 23.29 ± 1.52** | 8.13 ± 1.02 | 13.77 ± 2.15** |
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versus control group.
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