Research Article

Effect of Celastrol on Growth Inhibition of Prostate Cancer Cells through the Regulation of hERG Channel In Vitro

Table 1

Effects of Celastrol on cell cycle distribution and early apoptosis (, ±S).

CelastrolCell cycle (%)Apoptosis rate (%)
(μmol/L)G1/G0SG2/MSub-G1

0 (control)39.95 ± 1.8849.45 ± 1.6710.60 ± 1.332.88 ± 0.33
0.540.48 ± 2.3446.19 ± 1.8613.33 ± 1.841.69 ± 0.24
1.051.40 ± 1.96**37.67 ± 2.03**10.93 ± 0.983.25 ± 0.78
2.068.58 ± 2.89**23.29 ± 1.52**8.13 ± 1.0213.77 ± 2.15**

versus control group.