Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2015, Article ID 309478, 7 pages
http://dx.doi.org/10.1155/2015/309478
Research Article

Characterization of Multidrug Resistant Extended-Spectrum Beta-Lactamase-Producing Escherichia coli among Uropathogens of Pediatrics in North of Iran

1Nosocomial Infection Research Center, Mazandaran University of Medical Sciences, Buali Sina Hospital, Sari, Iran
2Department of Clinical Pharmacy, Faculty of Pharmacy, Thalassemia Research Center, Mazandaran University of Medical Sciences, Sari, Iran
3Molecular and Cell Biology Research Center, Department of Immunology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
4Department of Pharmacotherapy and Translational Research, University of Florida, Box 100486, Gainesville, FL 32610-0486, USA
5Fatemeh Zahra Hospital, Mazandaran University of Medical Sciences, Sari, Iran
6Department of Clinical Pharmacy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Km 18 Khazarabad Road, Khazar Square, Sari, Mazandaran 48471-16548, Iran

Received 23 June 2014; Revised 30 October 2014; Accepted 3 November 2014

Academic Editor: Madhab K. Chattopadhyay

Copyright © 2015 Mohammad Sadegh Rezai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. Girish, K. Saileela, and S. K. Mohanty, “Extended spectrum beta-lactamase producing Klebsiella pneumoniae and Escherichia coli in neonatal intensive care unit,” Journal of Bacteriology & Parasitology, vol. 3, p. 2, 2012. View at Google Scholar
  2. A. Poulou, E. Grivakou, G. Vrioni et al., “Modified CLSI extended-spectrum β-lactamase (ESBL) confirmatory test for phenotypic detection of ESBLs among Enterobacteriaceae producing various β-lactamases,” Journal of Clinical Microbiology, vol. 52, no. 5, pp. 1483–1489, 2014. View at Publisher · View at Google Scholar · View at Scopus
  3. M. A. Bhat, S. Sageerabanoo, R. Kowsalya, and G. Sarkar, “The occurrence of CTX-M3 type extended spectrum beta lactamases among Escherichia coli causing urinary tract infections in a tertiary care hospital in puducherry,” Journal of Clinical and Diagnostic Research, vol. 6, no. 7, pp. 1203–1206, 2012. View at Google Scholar
  4. A. Bhattacharjee, M. R. Sen, P. Prakash, A. Gaur, and S. Anupurba, “Increased prevalence of extended spectrum β lactamase producers in neonatal septicaemic cases at a tertiary referral hospital,” Indian Journal of Medical Microbiology, vol. 26, no. 4, pp. 356–360, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. P. A. Bradford, “Extended-spectrum β-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat,” Clinical Microbiology Reviews, vol. 14, no. 4, pp. 933–951, 2001. View at Publisher · View at Google Scholar · View at Scopus
  6. D. L. Paterson, K. M. Hujer, A. M. Hujer et al., “Extended-spectrum β-lactamases in klebsiella pneumoniae bloodstream isolates from seven countries: dominance and widespread prevalence of SHV- and CTX-M-Type β-lactamases,” Antimicrobial Agents and Chemotherapy, vol. 47, no. 11, pp. 3554–3560, 2003. View at Publisher · View at Google Scholar · View at Scopus
  7. P. Lal, A. Kapil, B. K. Das, and S. Sood, “Occurrence of TEM & SHV gene in extended spectrum β-lactamases (ESBLs) producing Klebsiella sp. isolated from a tertiary care hospital,” Indian Journal of Medical Research, vol. 125, no. 2, pp. 173–178, 2007. View at Google Scholar · View at Scopus
  8. J. Rodríguez-Baño, M. D. Navarro, L. Romero et al., “Clinical and molecular epidemiology of extended-spectrum β-lactamase. Producing Escherichia coli as a cause of nosocomial infection or colonization: implications for control,” Clinical Infectious Diseases, vol. 42, no. 1, pp. 37–45, 2006. View at Publisher · View at Google Scholar · View at Scopus
  9. J. Kim, S. G. Hong, I. K. Bae et al., “Emergence of Escherichia coli sequence type ST131 carrying both the bla GES-5 and bla CTX-M-15 genes,” Antimicrobial Agents and Chemotherapy, vol. 55, no. 6, pp. 2974–2975, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. S. A. Jemima and S. Verghese, “Multiplex PCR for blaCTX-M & blaSHV in the extended spectrum beta lactamase (ESBL) producing gram-negative isolates,” Indian Journal of Medical Research, vol. 128, no. 3, pp. 313–317, 2008. View at Google Scholar · View at Scopus
  11. E. Ruppé, S. Hem, S. Lath et al., “CTX-M β-lactamases in Escherichia coli from community-acquired urinary tract infections, Cambodia,” Emerging Infectious Diseases, vol. 15, no. 5, pp. 741–748, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. I. Shukla, R. Tiwari, and M. Agrawal, “Prevalence of extended spectrum β-lactamasee producing Klebsiella pneumoniae in a tertiary care hospital,” Indian Journal of Medical Microbiology, vol. 22, no. 2, pp. 87–91, 2004. View at Google Scholar · View at Scopus
  13. T. B. Y. Liem, M. Filius, P. D. van der Linden, R. Janknegt, S. Natsch, and A. G. Vulto, “3.1 Changes in antibiotic use in Dutch hospitals over a 6-year period: 1997–2002,” in Antimicrobial Drug Use in Hospitalized Children, vol. 63, p. 60, 2011. View at Google Scholar
  14. J. Oteo, V. Bautista, N. Lara et al., “Parallel increase in community use of fosfomycin and resistance to fosfomycin in extended-spectrum β-lactamase (ESBL)-producing Escherichia coli,” Journal of Antimicrobial Chemotherapy, vol. 65, no. 11, pp. 2459–2463, 2010. View at Publisher · View at Google Scholar · View at Scopus
  15. Liaison Representatives, “Practice parameter: the diagnosis, treatment, and evaluation of the initial urinary tract infection in febrile infants and young children. American Academy of Pediatrics. Committee on Quality Improvement. Subcommittee on Urinary Tract Infection,” Pediatrics, vol. 103, no. 4, pp. 843–852, 1999. View at Google Scholar
  16. F. R. Cockerill, Performance Standards for Antimicrobial Susceptibility Testing: Twenty-First Informational Supplement, Clinical and Laboratory Standards Institute (CLSI), 2011.
  17. P. Wayne, “Performance standards for antimicrobial susceptibility testing. Twenty firt informational supplement,” CLSI Document M100-S21, Clinical and Laboratory Standards Institute, 2011. View at Google Scholar
  18. A. Manoharan, K. Premalatha, S. Chatterjee, and D. Mathai, “Correlation of TEM, SHV and CTX-M extended-spectrum beta lactamases among Enterobacteriaceae with their in vitro antimicrobial susceptibility,” Indian Journal of Medical Microbiology, vol. 29, no. 2, pp. 161–164, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. L. Poirel, I. Le Thomas, T. Naas, A. Karim, and P. Nordmann, “Biochemical sequence analyses of GES-1, a novel class A extended-spectrum β-lactamase, and the class 1 integron In52 from Klebsiella pneumoniae,” Antimicrobial Agents and Chemotherapy, vol. 44, no. 3, pp. 622–632, 2000. View at Publisher · View at Google Scholar · View at Scopus
  20. M. Y. Alikhani, Z. Karimi Tabar, F. Mihani et al., “Antimicrobial resistance patterns and prevalence of blaPER-1 and blaVEB-1 genes among ESBL-producing Pseudomonas aeruginosa isolates in West of Iran,” Jundishapur Journal of Microbiology, vol. 7, no. 1, Article ID e8888, 2014. View at Publisher · View at Google Scholar · View at Scopus
  21. S. Benenson, S. Navon-Venezia, Y. Carmeli et al., “Carbapenemresistant Klebsiella pneumoniae endocarditis in a young adult. Successful treatment with gentamicin and colistin,” International Journal of Infectious Diseases, vol. 13, no. 5, pp. e295–e298, 2009. View at Publisher · View at Google Scholar
  22. Y. H. Lee, B. Cho, I. K. Bae, C. L. Chang, and S. H. Jeong, “Klebsiella pneumoniae strains carrying the chromosomal SHV-11 β-lactamase gene produce the plasmid-mediated SHV-12 extended-spectrum β-lactamase more frequently than those carrying the chromosomal SHV-1 β-lactamase gene,” Journal of Antimicrobial Chemotherapy, vol. 57, no. 6, pp. 1259–1261, 2006. View at Publisher · View at Google Scholar · View at Scopus
  23. B. Kochaksaraii, N. A. Omran, N. Javid, F. Shakeri, M. Yazdi, and E. Ghaemi, “Extended spectrum beta lactamase producing E.coli isolated from Gorgan, North of Iran,” Medical Laboratory Journal, vol. 6, no. 1, 2012. View at Google Scholar
  24. M. Moosavian and B. Deiham, “Distribution of TEM, SHV and CTX-M Genes among ESBL-producing Enterobacteriaceae isolates in Iran,” African Journal of Microbiology Research, vol. 6, pp. 5433–5439, 2012. View at Google Scholar
  25. L. Arbabi, M. Rahbar, M. Jabbari et al., “Extended-spectrum beta-lactamase-producing E. coli and Klebsiella pneumoniae isolated from urinary tract infections in Milad Hospital, Tehran, Iran,” HealthMED Journal, 2012. View at Google Scholar
  26. F. Shahcheraghi, V. S. Nikbin, and M. M. Feizabadi, “Prevalence of ESBLs genes among multidrug-resistant isolates of pseudomonas aeruginosa isolated from patients in Tehran,” Microbial Drug Resistance, vol. 15, no. 1, pp. 37–39, 2009. View at Publisher · View at Google Scholar · View at Scopus
  27. S. Ananthan and A. Subha, “Cefoxitin resistance mediated by loss of a porin in clinical strains of Klebsiella pneumoniae and Escherichia coli,” Indian Journal of Medical Microbiology, vol. 23, no. 1, pp. 20–23, 2005. View at Publisher · View at Google Scholar · View at Scopus
  28. C. Branger, O. Zamfir, S. Geoffroy et al., “Genetic background of Escherichia coli and extended-spectrum β-lactamase type,” Emerging Infectious Diseases, vol. 11, no. 1, pp. 54–61, 2005. View at Publisher · View at Google Scholar · View at Scopus
  29. S. Babypadmini and B. Appalaraju, “Extended spectrum β-lactamases in urinary isolates of Escherichia coli and Klebsiella pneumoniae—prevalence and susceptibility pattern in a tertiary care hospital,” Indian Journal of Medical Microbiology, vol. 22, no. 3, pp. 172–174, 2004. View at Google Scholar · View at Scopus
  30. S. Swerkersson, U. Jodal, C. Åhrén, and S. Hansson, “Urinary tract infection in small outpatient children: the influence of age and gender on resistance to oral antimicrobials,” European Journal of Pediatrics, vol. 173, no. 8, pp. 1075–1081, 2014. View at Publisher · View at Google Scholar · View at Scopus
  31. S. Benenson, S. Navon-Venezia, Y. Carmeli et al., “Carbapenem-resistant Klebsiella pneumoniae endocarditis in a young adult. Successful treatment with gentamicin and colistin,” International Journal of Infectious Diseases, vol. 13, no. 5, pp. e295–e298, 2009. View at Publisher · View at Google Scholar · View at Scopus
  32. Y.-H. Ku, M.-F. Lee, Y.-C. Chuang, C.-C. Chen, and W.-L. Yu, “In vitro activity of colistin sulfate against Enterobacteriaceae producing extended-spectrum beta lactamases,” Journal of Microbiology, Immunology and Infection, 2014. View at Publisher · View at Google Scholar · View at Scopus
  33. A. Walkty, M. DeCorby, K. Nichol, J. A. Karlowsky, D. J. Hoban, and G. G. Zhanel, “In vitro activity of colistin (polymyxin E) against 3,480 isolates of gram-negative bacilli obtained from patients in Canadian hospitals in the CANWARD study, 2007–2008,” Antimicrobial Agents and Chemotherapy, vol. 53, no. 11, pp. 4924–4926, 2009. View at Publisher · View at Google Scholar · View at Scopus
  34. A. A. Kader and A. K. Kumar, “Prevalence of extended spectrum β-lactamase among multidrug resistant gram-negative isolates from a general hospital in Saudi Arabia,” Saudi Medical Journal, vol. 25, no. 5, pp. 570–574, 2004. View at Google Scholar · View at Scopus
  35. F. Shahcheraghi, S. Nasiri, and H. Noveiri, “Detection of extended-spectrum β-lactamases (ESBLs) in Escherichia coli,” Iranian Journal of Clinical Infectious Diseases, vol. 4, no. 2, pp. 65–70, 2009. View at Google Scholar · View at Scopus
  36. P. M. Hawkey, “Prevalence and clonality of extended-spectrum β-lactamases in Asia,” Clinical Microbiology and Infection, vol. 14, no. 1, pp. 159–165, 2008. View at Publisher · View at Google Scholar · View at Scopus
  37. E. Salehifar, M. M. Nasehi, G. Eslami, S. Sahraei, and R. Alizadeh-Navai, “Determination of antibiotics consumption in Buali-Sina pediatric Hospital, Sari 2010-2011,” Iranian Journal of Pharmaceutical Research, vol. 13, no. 3, p. 995, 2014. View at Google Scholar
  38. G. L. French, K. P. Shannon, and N. Simmons, “Hospital outbreak of Klebsiella pneumoniae resistant to broad-spectrum cephalosporins and β-lactam-β-lactamase inhibitor combinations by hyperproduction of SHV-5 β-lactamase,” Journal of Clinical Microbiology, vol. 34, no. 2, pp. 358–363, 1996. View at Google Scholar · View at Scopus
  39. M. Edelstein, M. Pimkin, I. Palagin, I. Edelstein, and L. Stratchounski, “Prevalence and Molecular Epidemiology of CTX-M Extended-Spectrum β-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae in Russian Hospitals,” Antimicrobial Agents and Chemotherapy, vol. 47, no. 12, pp. 3724–3732, 2003. View at Publisher · View at Google Scholar · View at Scopus
  40. N. Mendonça, J. Leitão, V. Manageiro, E. Ferreira, and M. Caniça, “Spread of extended-spectrum β-lactamase CTX-M-producing Escherichia coli clinical isolates in community and nosocomial environments in Portugal,” Antimicrobial Agents and Chemotherapy, vol. 51, no. 6, pp. 1946–1955, 2007. View at Publisher · View at Google Scholar · View at Scopus