Effects of Berberine on Amelioration of Hyperglycemia and Oxidative Stress in High Glucose and High Fat Diet-Induced Diabetic Hamsters In Vivo

Figure 1

Influence of BBR on the weights of body and liver in diet-induced diabetic and hyperlipidemic hamsters. (a) The weights of diabetic and hyperlipidemic hamsters after medication. (b) Effects of BBR on the liver weight in the diabetic and hyperlipidemic hamsters. (c) Histological findings of the liver stained with Oil Red O. The paraffin slice and Oil Red O staining of hamsters’ liver tissues (×200). MC: model control, ; MET: metformin, ; SIM: simvastatin, ; BBR (low): low dose of BBR, ; BBR (high): high dose of BBR, . Data are presented as means ± SE. MET, SIM, BBR (low) and BBR (high) Versus MC: , ; versus MET: . One-way ANOVA.

(a)

(b)

(c)