Isoflurane Damages the Developing Brain of Mice and Induces Subsequent Learning and Memory Deficits through FASL-FAS Signaling

Figure 2

(a) Western blot showing the expression of FAS and FASL proteins in the hippocampus was increased by isoflurane compared with control group (). (b) Quantification of the western blot showed that isoflurane increased the expression of FAS protein in the mouse hippocampus compared to the wild control group. (c) Quantification of the western blot showed that isoflurane increased the expression of FASL protein in the mouse hippocampus compared to the wild control group. (d) Isoflurane increased the level of caspase-3 compared with the wild control group (). (e) Quantification of the western blot showed that isoflurane increased the expression of caspase-3 protein in the mouse hippocampus compared to the wild control group. Error bars represent the standard deviation (SD) of two independent experiments; .

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