Table 5: Comparisons of genotype data between presence/absence of cancer history stratified by smoking-related phenotypes.

GenotypeGenotypic modelDominant modelRecessive model
TTTCCCOR (95% CI)aOR (95% CI)a

Smoking history
Ever-smokers
 Cancer1765403.281788 0.19381 1.017 (0.659–1.570)0.005743 0.93959 0.617 (0.349–1.090)2.805891 0.09392
 Control79175126
Never-smokers
 Cancer1650251.234473 0.53943 1.299 (0.782–2.159)1.022436 0.31194 0.966 (0.530–1.761)0.012551 0.91080
 Control68184124
Smoking period (year)
Long (≥44)
 Cancer1331240.392140 0.82195 1.226 (0.635–2.365)0.181513 0.67008 1.226 (0.635–2.365)0.341154 0.55916
 Control438662
Short (<44)
 Cancer434165.917681 0.05188 1.226 (0.635–2.365)0.369160 0.54346 0.338 (0.115–0.996)4.191842 0.04062
 Control368864
CPDb
High (>20)
 Cancer919121.526609 0.46612 1.642 (0.743–3.630)1.514011 0.21853 1.194 (0.484–2.946)0.147578 0.70086
 Control183638
Low (≤20)
 Cancer846285.512995 0.06351 0.849 (0.504–1.428)0.382380 0.53633 0.402 (0.184–0.880)5.491155 0.01911
 Control6113988
Brinkman (smoking) index
High (>700)
 Cancer1233241.322869 0.51611 0.961 (0.536–1.723)0.017720 0.89410 0.671 (0.330–1.365)1.223659 0.26864
 Control437661
Low (≤700)
 Cancer532163.103819 0.21184 1.130 (0.586–2.181)0.133278 0.71506 0.469 (0.174–1.261)2.341073 0.12600
 Control369765

Odds ratio (95% confidence interval).
bCigarettes smoked per day.
Significant association between the minor T allele of the SNP and noncancer status (present or past illness) in the recessive model () in subjects whose smoking duration is short.
Significant association between the minor T allele of the SNP and noncancer status (present or past illness) in the recessive model () in subjects whose CPD rate is low.