Molecular PET Imaging of Cyclophosphamide Induced Apoptosis with 18F-ML-8
(a) Chemical synthesis of ML-8 (9) and its precursor (7) starting from 3-bromo-propanol and diethyl malonate. (b) Radiosynthesis of 18F-ML-8 from the precursor (7). O-TBDMS = O-tert butyl dimethyl silyl; O-Et = O-ethyl; O-Ms = O-mesyl.
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