Single Nucleotide Polymorphisms of the GJB2 and GJB6 Genes Are Associated with Autosomal Recessive Nonsyndromic Hearing Loss

Table 4

Hardy-Weinberg proportions in the groups studied.

Gene	SNP	HWE P value (CTL)	HWE value (patients)
GJB2	rs3751385	0.143	0.001
	rs7994748	0.711
	rs7329857	0.994	0.615
	rs7987302	0.917	0.895
GJB6	rs7322538	0.740	0.435
	rs9315400	0.653	0.557
	rs877098
	rs945369	0.0082	0.003
	rs7333214	0.995	0.156

HWE: Hardy-Weinberg equilibrium test was done using Pearson’s goodness of fit test and value <0.05 was considered to show significant deviation of the observed genotypes from Hardy-Weinberg proportions. Significant deviations values from Hardy-Weinberg equilibrium are shown in boldface.