Environmental Trigger(s) of Type 1 Diabetes: Why So Difficult to Identify?

Table 1

HLA typing and time points for follow-up with blood samples in MIDIA.

(a) Eligible HLA type	DRB1^*03-DQA1^*05-DQB1^*02/DRB1^*0401-DQA1^*03-DQB1^*0302
(b) Time points for blood samples	3, 6, 9, and 12 months, thereafter annually; If positivity for one autoantibody, a new blood sample after 6 months. If positivity for two or three autoantibodies, a new samples after 3 months
(c) Questionnaires	Collected at 3, 6, 9, and 12 months and thereafter annually
(d) Stool samples	Collected each month from 3 months to 3 years of age